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Princep Liquid (Simazine 4L)
06/10/26
Princep Liquid, manufactured by Syngenta, was formerly called Simazine 4L is a pre-emergent herbicide that controls many different common weeds like Poa Annua, Ragweed, Crabgrass, and over 40 other broadleaf and annual grassy weeds.
This product will control weeds before they emerge, but will not kill weeds that have already emerged. Princep can even be used in crop fields to protect your plants from weeds.
Tools Needed:
To use Princep Liquid, you will need spraying equipment. For a small volume application, you can use a pump sprayer, a backpack sprayer or a hose-end sprayer. For large volume application, you can apply using a professional skid sprayer.
How to Use:

- Step 1: Figure out how much Princep Liquid you will need by calculating the size of the treatment area. To do this, measure and multiply the area's length x width to get the total square footage to be treated. Princep Liquid treatments should be applied at a rate of 0.75 to 1.5 fl. oz. in a gallon of water per 1,000 sq. ft. on turfgrass. For large volume applications, apply 1 to 2 quarts of Princep Liquid per 20 gallons of water per acre. For example, if you measured 3,500 sq. ft. of area to be treated you will need to mix between 2.62 to 5.25 fl. oz. of Princep in at least 3.5 gallons of water.
- Step 2: Fill your sprayer halfway with water. Measure the required amount of product and add it to the sprayer. Fill your sprayer with the rest of the water and thoroughly agitate it and you’re ready to apply.
- Step 3: Apply the product over the desired area, preferably on a fan spray setting for uniform coverage. Reapply as needed, following label instructions regarding your application type.
Where to Use:
Princep can be applied on residential and commercial lawns and common plant growing areas like nurseries, crop fields and more. Refer to the label for a full list of applicable locations.
When to Use:
Princep Liquid is typically applied in late fall before the regular rains to prevent weed germination. Princep is most commonly used as a soil application over plants that are already established, so it may not be the best option for plants that are still young. Refer to the label for proper application timings, as they can vary depending on the climate, targeted weed, and application method.
Safety Information:
Princep is safe to use around children and pets when applied according to the product label instructions. Always wear the proper personal protective equipment (PPE) when mixing and applying this product.
Wait until 48 hours have passed after application before allowing children, pets, and workers to enter treated areas.
It is important to prevent any drift of this product from getting into non-target areas, as it can contaminate water or harm non-target plants.
Special Considerations:
It is recommended not to apply Princep Liquid to sand and loamy sand soils because the active ingredient Simazine can travel or leach through soil and can enter groundwater.
| Restricted Use | No |
|---|---|
| Shipping Restrictions | AK, DC, IL |
| Signal Word | CAUTION |
| Keith's Pro Tip | "Pre-emergent herbicides only control weeds that have not sprouted, and will not kill weeds that are already in place. It may be helpful to pair a pre-emergent herbicide with an approved post-emergent herbicide to control both established weeds and prevent them from growing back." |
| Target Pests Multi | Alyssum, Annual Bluegrass, Annual Ryegrass, Bur Clover, Carelessweed, Carpetweed, Chickweed, Common Groundsel, Common Lambsquarters, Crabgrass, Fall Panicum, Fescue, Fiddleneck, Filaree, Fireweed, Fivehook Bassia, Flora's Paintbrush, Foxtail, Goosegrass, Henbit, Junglerice, Knawel, Nightshade, Pepperweed, Pineapple_Weed, Prickly Lettuce, Purslane, Ragweed, Remaids, Shepherdspurse, Signalgrass, Silver Hairgrass, Smartweed, Spanishneedles, Speedwell, Tansy Mustard, Thistle, Wild Morning-glory, Wild Oats, Witchgrass, Yellow Flower Pepperweed |
| Time to Kill | Because this prevents weeds from growing, the time frame can vary depending on the weed and grass type. This product prevents weeds from germinating, so it lasts for the majority of a season and may need to be reapplied in 3-5 months. |
| Chemical Type | Herbicide |
| Formulation | Suspended Concentrate |
| Application Methods | Broadcast Spray, Injection, Spot Treatment |
| Product Drawbacks | This product is a pre-emergent herbicide which means it will not kill weeds that are established, or have already sprouted. This product is a prevention tool to stop the regrowth and spreading of weeds. |
| Active Ingredient | Simazine 41.9% |
| Application Equipment | Backpack Sprayer, Gloves, Hose End Sprayer, Pump Sprayer, Respirator Mask, Spray Rig |
| Mix Rate | The application rate of this product can varying depending on soil type, plant type, and weed type. In most cases, we suggest using 1-2 quarts of product per acre. Refer to the label for a complete list of mix rates for your target pest, and plant type. |
| Use Sites | Outdoors |
| Yield | Depending on your mix rate, one 2.5 gallon bottle of Simazine may treat around 10 acres. |
| EPA Registration No. | 100-526 |
| Shelf Life | This product may last up to two years when stored properly in a cool, dry location. |
| Comparable Products | Oryzalin 4 Pro, Dithiopyr 40 WSP |
| Children or pets? | No |
| Property Characteristics | None |
| Restricted Use | No |
| Brand | SYNGENTA |
| Keith's Pro Tips | "Pre-emergent herbicides only control weeds that have not sprouted, and will not kill weeds that are already in place. It may be helpful to pair a pre-emergent herbicide with an approved post-emergent herbicide to control both established weeds and prevent them from growing back." |
| Product Drawbacks | This product is a pre-emergent herbicide which means it will not kill weeds that are established, or have already sprouted. This product is a prevention tool to stop the regrowth and spreading of weeds. |
| Target Pests | alyssum, annual bluegrass, annual morningglory, annual ryegrass, barnyardgrass, burclover, carelessweed, carpetweed, common chickweed, common lambsquarters, common purslane, crabgrass, downy brome, fall panicum, fiddleneckfilaree, fireweed, fivehook bassia, Flora’s paintbrush, Florida pusley, foxtails, goosegrass, groundsel, henbit, junglerice, knawel, nightshade, pepperweed, pigweed, pineappleweed, prickly lettuce, ragweed, rattail fescue, redmaids, Russian thistle, shepherdspurse, signalgrass, silver hairgrass, smartweed, spanishneedles, speedwell, tansymustard, wild mustard, wild oats, witchgrass, and yellow flower pepperweed. |
| Application Equipment | Backpack Sprayer, Gloves, Hose End Sprayer, Pump Sprayer, Respirator Mask, Spray Rig |
| Application Methods | Broadcast Spray, Injection, Spot Treatment |
| Active Ingredient | Simazine 41.9% |
| Product Type | Herbicide |
| Formulation | Suspended Concentrate |
| Application Rate | The application rate of this product can varying depending on soil type, plant type, and weed type. In most cases, we suggest using 1-2 quarts of product per acre. Refer to the label for a complete list of mix rates for your target pest, and plant type. |
| Shelf Life | This product may last up to two years when stored properly in a cool, dry location. |
| Yield | Depending on your mix rate, one 2.5 gallon bottle of Simazine may treat around 10 acres. |
| Use Sites | Outdoors |
| Time to Kill | Because this prevents weeds from growing, the time frame can vary depending on the weed and grass type. This product prevents weeds from germinating, so it lasts for the majority of a season and may need to be reapplied in 3-5 months. |
| Comparable Products | Oryzalin 4 Pro, Dithiopyr 40 WSP |
| Use Caution On | Zoysiagrass |
| EPA Registration # | 100-526 |



